The Signature Supplement™ test results will show if your client has a tendency
for imbalance in any of the following metabolic systems:

A synopsis of each of these metabolic conditions and their expression follows:

1. IMPAIRED GLUCOSE CONTROL can result in a condition of low blood sugar or low blood glucose. Generally to rectify this imbalance requires intelligent food choices as well as supplementation. All carbohydrates (sugars and starches) turn into glucose in the process of digestion. Glucose in the blood provides the energy needed for many functions of the body and brain. Simple carbohydrates such as certain fruits and processed foods made from white flour, (pasta, white bread, cookies, cakes, etc.) and or sugar can cause blood glucose imbalances by delivering too much glucose to the blood stream at one time. A diet too high in refined carbohydrates, caffeine or other stimulants will stimulate the production of excess insulin. This pattern can cause wide variations in blood glucose levels, which results in an uneven supply of energy to the cells of the body and brain. These biochemical swings can lead to mood swings, fainting attacks, shakiness between meals, and sometimes, constant fatigue and drowsiness after meals. Individuals with this issue have a genetic tendency to be depleted in chromium, biotin and manganese. These supplements help stabilize glucose levels. Complex carbohydrates such as whole grains, beans, certain fruits and vegetables help maintain a more gradual and moderate absorption of glucose in the body without the more uneven biochemical swings.

The Individualized Nutritional Profile and the specific nutrients contained in their unique Signature Supplement™ formula can be helpful in balancing these tendencies. This imbalance needs both a supplement and a conscious healthy food program to rebalance the system. Both the foods that they eat, as well as the supplements they take, directly affect the balancing of this system. An estimated 41 million Americans have ‘pre-diabetes’, or impaired glucose tolerance, in which blood sugar levels are higher than normal and lead to high risk of developing type 2 diabetes. A recent study at the University of Michigan showed that in just three years, the risk of developing type 2 diabetes was reduced by 58 per cent among those in the lifestyle change group using nutritional support, diet and exercise.

2. MALABSORPTION This results in an inefficient processing of foods by the digestive system and poor absorption into the bloodstream. Even though one’s diet may be adequate, malabsorption may result in various nutritional deficiencies. “You are what you absorb, not necessarily what you eat.” Holds true for this imbalance. Client’s with this imbalance can exhibit slenderness during childhood and teen years, adult slenderness despite a normal food intake, stomach or intestinal discomfort and pain, episodes of diarrhea or constipation, excessive stomach or intestinal gas, constant feeling of hunger, and cravings.

There are three primary classes of absorption problems: (1) stomach problems, including excessive or insufficient HCl levels, (2) incomplete digestion in the small intestine, and (3) problems at the brush-border of the intestine where most nutrients are absorbed into the portal blood stream. The consequences can include nutrient deficiencies, a compromised immune system, irritation of the intestinal tract, candida, and mental health problems. Incomplete breakdown of protein and fats can adversely affect brain neurotransmission, and is associated with impulsivity and academic underachievement. Client’s may experience ongoing hunger as their body signals for more nutrients through consuming greater quantities of foods.

In this particular profile, promoting harmony in the stomach and intestines will help the client’s body use food and liquids properly. Most likely their body does not produce enough digestive enzymes to assist in breaking down and absorbing their food. Many other habits can inadvertently sabotage the digestive system in those with this imbalance. Because of this imbalance those with this issue are more sensitive to stress, and other associated environmental factors that can affect digestion. Their emotional sensitivity has a direct effect on stomach acid secretion.

Drinking warm liquids before a meal is suggested, avoiding iced liquids is recommend and no liquids should be consumed with food. This will stop the inadvertent dilution of digestive fluids. Additional digestive enzymes can also assist in creating a healthier digestive environment. There are certain foods and supplements to avoid and others that should be emphasized to enhance the digestion, absorption and assimilation of food. These client’s may have sub acute food allergies, which can affect the digestive process.

We suggest that you speak with your client for further testing of potential food allergies. Over all clients are best served by an integrated holistic approach using both proper supplementation as well as employing healthy lifestyle eating habits. This would entail eating their meals in a quiet peaceful location without stress. A few quiet moments before a meal with several deep slow abdominal breaths can help calm their system and prepare it to digest their meal. They need to plan ahead for their meals so that they are not rushed either in preparing or eating them. Individuals with this condition have a genetic tendency to depleted in biotin, betaine, pepsin, and gastric lipase. They are also overloaded in manganese and need to avoid ingesting more amounts. More information is available in their individualized Nutritional Profile.



3. IMPAIRED METAL METABOLISM Also known as oxidative stress may result in a special need for specific mineral supplements and the avoidance of others in your client’s supplement as well as in their foods. Heavy metal metabolism can occur when too many heavy metals are absorbed into their system. A specific protein (metallothionine) usually begins to manage the heavy metals that they ingest. Many health issues are attributed to this abundance of heavy metals and lack of others. Your client’s reaction to this is personal and likely to occur in organs or metabolic systems that have a weakness or a tendency to become imbalanced. This is one of those undiagnosed health issues that goes untreated because the underlying associated issues are often overlooked. We recommend going to the associated issues with a two-pronged approach. Gradually encourage the body to reduce the heavy metals and rebuild the protein metallothionine so that it protects the body from further over saturation of heavy metals.

Several dozen metallic elements have an important influence on human biochemistry and brain chemistry. The most important nutrient metals include zinc, copper, calcium, magnesium, iron, selenium, lithium, cobalt, manganese, and phosphorus and the electrolytes sodium and potassium. In addition, toxic heavy metals such as lead, cadmium and mercury can disrupt brain chemistry and human functioning. Serious problems can result if abnormal levels of any of the above metals are present. The body has several mechanisms which regulate and control these metal concentrations and cope with fluctuations in dietary intake.

Divalent metals such as copper, zinc, and manganese would be very toxic to cells in elemental or ionic form. These metals are "enveloped" or "bound" to a small linear protein (61 amino acids) called metallothionine (MT), which supervises and regulates metal levels in blood, brain and the periphery. The various metals in the body compete with each other for participation in chemical reactions and can displace each other depending on local concentration and their relative position in the chemical activity series. Thus, an overload or deficiency of one metal can alter the concentration and functioning of other metals.

Expressions of oxidative stress range from a weakened immune system, concentration and memory problems, sleep difficulties, mood swings, and lack of energy to unhealthy skin, hair and nails. High-copper individuals usually have a history of hyperactivity, tinnitus, and skin sensitivity to metals. They may also exhibit quick, over - reactive tempers, symptoms of ADD, ADH, and have a hyperactive personality. Females with this condition usually have significant PMS and are prone to heightened depression during hormonal events such as childbirth and menopause. They often report a worsening of depression after estrogen or off the shelf multiple vitamins. Treatment focuses on release of excess copper from tissues, promotion of copper excretion, and stimulation of metallothionein (a metal-binding protein) production. Their individualized profile and unique supplement formula can provide your client with a balanced nutrition program to optimize their health.



4. IMBALANCED AMINO ACID METABOLISM is associated with elevated histamine levels and under methylation. Histamine is an important brain neurotransmitter, which may influence personality and behavioral traits. They are under-methylated which is associated with low serotonin levels. Methylation is a process, which impacts the production of serotonin, dopamine and other neurotransmitters. Without enough serotonin it is difficult for someone to have a happy day, it is our “feel good” neurotransmitter. This syndrome often involves seasonal variations in depression, obsessive-compulsive behavior, inhalant allergies, and frequent headaches. They have a genetic tendency to be very depressed in calcium, magnesium, methionine, and Vitamin B-6 with excessive levels of folic acid. Individuals with this imbalance usually have too much of several specific nutrients that they should not consume in a supplement. This over abundance can prohibit other bio-chemical functions from occurring. The biochemical systems in our body are so interrelated that an abundance or lack of a needed nutrient can cause a cascading effect on other systems and create multiple signs of ill health.

5. IMBALANCED AMINO ACID METABOLISM is associated with lower blood histamine levels. This results in an individual being over-methylated which results in excessive amounts of dopamine, norepinephrine and serotonin. Histamine is an important brain neurotransmitter, which may influence personality and behavior traits. Extreme low-histamine individuals are usually nervous, anxious individuals who are prone to paranoia and despair. They are over-methylated which results in elevated dopamine and norepinephrine levels. Although free of seasonal allergies, they often report a multitude of food and chemical sensitivities. Many have a history of hyperactivity, learning disabilities, and underachievement. They can feel anxious, paranoid and depressed. Most individuals with this issue tend to be physically attractive and more creative than the rest of the population. Low histamine individuals tend to overreact to life experiences and dwell on the negative but are compassionate caregivers and non-competitive, accepting individuals. They have a genetic tendency to be very depressed in folates, niacin, and Vitamin B-12, and biochemical treatment focuses on supplementation of these nutrients. These persons are also overloaded in copper and methionine and supplements and foods with these nutrients must be strictly avoided. The individualized Nutritional Profile and Signature Supplements are designed to rebalance their biochemistry and optimize the performance of their metabolic systems.